Born in Chiba in 1971. Graduated from the Faculty of Law, Tohoku University. In 2000, he won the 5th Shincho Mystery Club Award for his debut novel Audubon's Prayer. His novel The Foreign Duck, the Native Duck and God in a Coin Locker won the 25th Yoshikawa Eiji Literary Prize for New Writers, and his short story, The Precision of the Agent of Death, won the 57th Mystery Writers of Japan Award. In 2008, he won the 5th Japan Booksellers' Award and the 21st Yamamoto Shugoro Prize for Remote Control (Japanese title Golden Slumber). In 2014, Isaka won the University Readers' Award for Bullet Train (Japanese title Maria Beetle). In 2017, his novel The Mantis (Japanese title AX) won the Shizuoka Bookstore Award (Novel Category). In 2020, he won the Shibata Renzaburo Award for Reverse Socrates. His numerous titles include Lush Life, A Cheerful Gang Turns the Earth, Gravity's Clowns, 3 Assassins (Japanese title Grasshopper), Desert, The Fool at the End of the World, Modern Times, The Mantis (Japanese title AX), Hotel Lucky Seven (Japanese title 777), and Goodbye Jabberwock. Isaka's books have been translated and published in about 19 countries worldwide. Maria Beetle was adapted into the major motion picture Bullet Train, starring Brad Pitt, in 2022. It has also been adapted into films and TV series in China and South Korea.